Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 4/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | IL1B | P01584 | 2/20 | 0.35 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | IRAK3 | Q9Y616 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984876 | 0.90 | CRBN (0.42) | CRBNARDDB1IKZF3ALDH1A1 | |
| SCHEMBL30985086 | 0.90 | CRBN (0.43) | CRBNARDDB1IKZF3IRAK1 | |
| SCHEMBL30985183 | 0.87 | CRBN (0.41) | CRBNARDDB1IKZF3IRAK1 | |
| SCHEMBL30985136 | 0.84 | CRBN (0.62) | CRBNARDDB1IKZF3TNF | |
| SCHEMBL27344039 | 0.83 | CRBN (0.50) | CRBNARDDB1IKZF3TNF | |
| SCHEMBL30984888 | 0.82 | CRBN (0.59) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL27462926 | 0.81 | CRBN (0.48) | CRBNARDDB1IKZF3TNF | |
| SCHEMBL30985002 | 0.81 | CRBN (0.59) | CRBNESR1 | |
| SCHEMBL30984870 | 0.81 | CRBN (0.41) | CRBNARDDB1IRAK1IRAK4 | |
| SCHEMBL30984987 | 0.79 | CRBN (0.64) | CRBNARDDB1IKZF3TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |