Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984870 | 0.94 | CRBN (0.41) | CRBNESR1ARBTKDDB1 | |
| SCHEMBL30985064 | 0.87 | CRBN (0.42) | CRBNESR1ARBTKDDB1 | |
| SCHEMBL30984709 | 0.85 | CRBN (0.59) | CRBNARBTKDDB1CDK9 | |
| SCHEMBL27344039 | 0.81 | CRBN (0.50) | CRBNARDDB1IKZF3 | |
| SCHEMBL30984742 | 0.80 | CRBN (0.61) | CRBNARBTKDDB1CDK9 | |
| SCHEMBL21480820 | 0.79 | CRBN (0.50) | CRBNESR1DDB1IKZF3 | |
| SCHEMBL30984876 | 0.78 | CRBN (0.42) | CRBNARDDB1ALKIKZF3 | |
| SCHEMBL30985086 | 0.77 | CRBN (0.43) | CRBNARDDB1IRAK1IRAK4 | |
| SCHEMBL30985067 | 0.77 | CRBN (0.51) | CRBNESR1ARDDB1IKZF3 | |
| SCHEMBL22873398 | 0.75 | CRBN (0.54) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |