Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984930 | 0.78 | HSD17B10 (0.39) | PARP1HSD17B10ALDH1A1 | |
| SCHEMBL30905935 | 0.77 | HTR3E (0.49) | PARP1TNK1HSD17B10ALDH1A1PRKCI | |
| SCHEMBL30984964 | 0.77 | CYP3A4 (0.36) | PARP1TNK1HSD17B10ALDH1A1PRKCI | |
| SCHEMBL30544687 | 0.76 | POLB (0.49) | PARP1HSD17B10ALDH1A1PRKCIPDE4B | |
| SCHEMBL30544684 | 0.76 | PIK3CD (0.53) | PARP1HSD17B10ALDH1A1PRKCIPDE4B | |
| SCHEMBL30984892 | 0.73 | ACACB (0.55) | PARP1CYP3A4 | |
| SCHEMBL30985003 | 0.72 | KMT2A (0.45) | ALDH1A1TDP1JAK2 | |
| SCHEMBL30544653 | 0.71 | TIPARP (0.45) | PARP1HSD17B10ALDH1A1PRKCIPDE4B | |
| SCHEMBL30984861 | 0.70 | KMT2A (0.45) | ALDH1A1TDP1 | |
| SCHEMBL30544700 | 0.70 | PIM1 (0.42) | PARP1TNK1HSD17B10ALDH1A1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |