Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247587 | 0.81 | SIRT6 (0.73) | CRBNMAPTALDH1A1SIRT6POLB | |
| SCHEMBL18283605 | 0.81 | MAPT (0.58) | CRBNMAPTALDH1A1SIRT6POLB | |
| SCHEMBL21526328 | 0.81 | SIRT6 (0.64) | CRBNMAPTALDH1A1SIRT6POLB | |
| SCHEMBL22466180 | 0.81 | MAPT (0.57) | CRBNMAPTALDH1A1SIRT6POLB | |
| SCHEMBL25366550 | 0.80 | SIRT6 (0.67) | CRBNMAPTALDH1A1SIRT6POLB | |
| SCHEMBL22471328 | 0.80 | SIRT6 (0.67) | CRBNMAPTALDH1A1SIRT6POLB | |
| SCHEMBL10035909 | 0.80 | SIRT6 (0.71) | CRBNMAPTALDH1A1SIRT6POLB | |
| SCHEMBL15271381 | 0.79 | SIRT6 (0.81) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL6151230 | 0.79 | SIRT6 (0.81) | MAPTALDH1A1SIRT6POLBADRB1 | |
| SCHEMBL10036165 | 0.79 | SIRT6 (0.65) | CRBNMAPTALDH1A1SIRT6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |