Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.45 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 5/20 | 0.43 |
| ▸ | JAK3 | P52333 | 5/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115690 | 1.00 | AXL (0.55) | AXLPRKCINUDT1MAP2K1TTBK1 | |
| SCHEMBL20956198 | 0.86 | AXL (0.50) | AXLPRKCINUDT1JAK1JAK3 | |
| SCHEMBL566667 | 0.86 | NUDT1 (0.65) | AXLPRKCINUDT1JAK1JAK3 | |
| SCHEMBL29477133 | 0.86 | NUDT1 (0.65) | AXLPRKCINUDT1JAK1JAK3 | |
| SCHEMBL30823440 | 0.86 | AXL (0.50) | AXLPRKCINUDT1MAP2K1JAK1 | |
| SCHEMBL20956169 | 0.86 | AXL (0.50) | AXLPRKCINUDT1MAP2K1JAK1 | |
| SCHEMBL31120987 | 0.85 | JAK3 (0.50) | AXLPRKCINUDT1JAK1JAK3 | |
| SCHEMBL20956013 | 0.85 | JAK3 (0.50) | AXLPRKCINUDT1JAK1JAK3 | |
| Hydrochloric Acid SCHEMBL29477135 | 0.85 | NUDT1 (0.64) | AXLPRKCINUDT1JAK1JAK3 | |
| Hydrochloric Acid SCHEMBL29234028 | 0.85 | NUDT1 (0.64) | AXLPRKCINUDT1JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525018-A | Bialkyne compound and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-08-20 | — | — | CN | disclosed |
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |