Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207769 | 0.65 | APOBEC3A (0.35) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19659321 | 0.61 | ALDH1A1 (0.33) | SMN1; SMN2 | |
| SCHEMBL25410612 | 0.58 | DPP4 (0.32) | — | |
| SCHEMBL1146219 | 0.57 | TSHR (0.38) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2032392 | 0.54 | TSHR (0.36) | SMN1; SMN2 | |
| Potassium SCHEMBL30932480 | 0.54 | TSHR (0.36) | SMN1; SMN2 | |
| SCHEMBL29223372 | 0.54 | TSHR (0.36) | SMN1; SMN2 | |
| SCHEMBL14163228 | 0.54 | TDP1 (0.42) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3936891 | 0.54 | SMN1; SMN2 (0.34) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6856109 | 0.54 | TDP1 (0.42) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397309-A2 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | F. Hoffmann-La Roche AG (CH) | 2024-07-10 | — | — | EP | disclosed |