SCHEMBL30985347

SCHEMBL30985347

O=C(CCl)NC1CCc2ccccc21

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.83
MTNR1A P48039 1/20 0.60
MTNR1B P49286 1/20 0.60
TAS1R3 Q7RTX0 1/20 0.58
TAS1R1 Q7RTX1 1/20 0.58
TAS1R2 Q8TE23 1/20 0.58
EPHX2 P34913 2/20 0.56
TSHR P16473 2/20 0.56
HPGD P15428 2/20 0.56
POLB P06746 2/20 0.54
DHODH Q02127 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HTT P42858 4/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PDPK1 O15530 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4858887 1.00 ALDH1A1 (0.83) ALDH1A1MTNR1AMTNR1BTAS1R3TAS1R1
SCHEMBL4866618 1.00 ALDH1A1 (0.83) ALDH1A1MTNR1AMTNR1BTAS1R3TAS1R1
SCHEMBL14698658 1.00 ALDH1A1 (0.83) ALDH1A1MTNR1AMTNR1BTAS1R3TAS1R1
SCHEMBL53323 0.91 ALDH1A1 (1.00) ALDH1A1TAS1R3TAS1R1TAS1R2TSHR
SCHEMBL606143 0.91 ALDH1A1 (1.00) ALDH1A1TAS1R3TAS1R1TAS1R2TSHR
SCHEMBL5969797 0.87 ALDH1A1 (0.64) ALDH1A1TAS1R3TAS1R1TAS1R2EPHX2
SCHEMBL21766236 0.87 ALDH1A1 (0.64) ALDH1A1TAS1R3TAS1R1TAS1R2EPHX2
SCHEMBL7154380 0.87 ALDH1A1 (0.64) ALDH1A1TAS1R3TAS1R1TAS1R2EPHX2
SCHEMBL25106886 0.86 ALDH1A1 (0.62) ALDH1A1TAS1R3TAS1R1TAS1R2EPHX2
SCHEMBL5970025 0.84 ALDH1A1 (0.61) ALDH1A1TAS1R3TAS1R1TAS1R2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113660932-B Phenyl derivatives having pendant alkyl and alkenyl extensions and pharmaceutical compositions comprising the same 景凯生物科技股份有限公司 2024-07-12 CN disclosed