SCHEMBL30985352

SCHEMBL30985352

COC(=O)CCCCCCC(=O)NC1CCc2cc(Br)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.55
CA7 P43166 1/20 0.55
CA14 Q9ULX7 1/20 0.55
HDAC6 Q9UBN7 5/20 0.46
HDAC3 O15379 4/20 0.46
HDAC1 Q13547 4/20 0.46
TBXA2R P21731 1/20 0.45
PTGER4 P35408 1/20 0.45
TRPV1 Q8NER1 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HTR1A P08908 1/20 0.40
DRD2 P14416 1/20 0.40
HTR7 P34969 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22516689 1.00 CA12 (0.55) CA12CA7CA14HDAC6HDAC3
SCHEMBL22516708 0.93 CA12 (0.48) CA12CA7CA14MEN1KMT2A
SCHEMBL22517019 0.88 CA12 (0.56) CA12CA7CA14HDAC6HDAC3
SCHEMBL22500094 0.87 CA12 (0.55) CA12CA7CA14HDAC6HDAC3
SCHEMBL22517090 0.87 CA12 (0.58) CA12CA7CA14HDAC6HDAC3
SCHEMBL22516731 0.86 CA12 (0.58) CA12CA7CA14HDAC6HDAC3
SCHEMBL25651 0.85 CA12 (0.47) CA12CA7CA14HDAC6HDAC3
SCHEMBL22517056 0.81 BDKRB1 (0.50) CA12CA7CA14MEN1KMT2A
SCHEMBL30985311 0.81 BDKRB1 (0.50) CA12CA7CA14MEN1KMT2A
SCHEMBL22500199 0.81 BDKRB1 (0.52) CA12CA7CA14MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113660932-B Phenyl derivatives having pendant alkyl and alkenyl extensions and pharmaceutical compositions comprising the same 景凯生物科技股份有限公司 2024-07-12 CN disclosed