Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30986385 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL16431683 | 0.83 | MAPT (0.55) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL25321839 | 0.80 | KDM4E (0.49) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL31078181 | 0.80 | KDM4E (0.49) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL7951081 | 0.77 | MAPT (0.55) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL1990199 | 0.77 | MAPK1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL4268905 | 0.75 | HTT (0.49) | ALDH1A1MAPTKMT2AMEN1HTT | |
| SCHEMBL29502548 | 0.75 | HTT (0.49) | ALDH1A1MAPTKMT2AMEN1HTT | |
| Hydrochloric Acid SCHEMBL8964835 | 0.74 | HTT (0.47) | ALDH1A1MAPTKMT2AMEN1HTT | |
| SCHEMBL3341055 | 0.74 | MEN1 (0.46) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642773-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024141444-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | disclosed |