Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22785775 | 0.87 | HDAC3 (0.53) | NPSR1L3MBTL1CA1PPARACA2 | |
| SCHEMBL30987118 | 0.85 | NPSR1 (0.48) | NPSR1L3MBTL1PPARACTSSHDAC3 | |
| SCHEMBL16633128 | 0.85 | CA1 (0.47) | NPSR1L3MBTL1CA1PPARACA2 | |
| SCHEMBL16633129 | 0.85 | CA1 (0.47) | NPSR1L3MBTL1CA1PPARACA2 | |
| SCHEMBL30819017 | 0.83 | L3MBTL1 (0.47) | NPSR1L3MBTL1CA1PPARACA2 | |
| SCHEMBL30819037 | 0.83 | L3MBTL1 (0.47) | NPSR1L3MBTL1CA1PPARACA2 | |
| SCHEMBL31127362 | 0.83 | NPSR1 (0.47) | NPSR1L3MBTL1CA1PPARACA2 | |
| SCHEMBL30819090 | 0.83 | NPSR1 (0.47) | NPSR1L3MBTL1CA1PPARACA2 | |
| SCHEMBL24323788 | 0.81 | CA1 (0.50) | NPSR1L3MBTL1CA1PPARACA2 | |
| SCHEMBL7053417 | 0.81 | CA1 (0.50) | NPSR1L3MBTL1CA1PPARACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646265-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | Insmed Incorporated (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |