Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24878867 | 1.00 | CYP3A4 (0.42) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL27457195 | 0.88 | ALDH1A1 (0.31) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL27458233 | 0.86 | ALDH1A1 (0.30) | ALDH1A1MAPK1 | |
| SCHEMBL24879349 | 0.84 | KDM4E (0.40) | TDP1ALDH1A1LMNAHSD17B10PARP1 | |
| SCHEMBL31723337 | 0.83 | CYP3A4 (0.42) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL27453451 | 0.80 | TNF (0.41) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL24878856 | 0.80 | TNF (0.42) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL24879034 | 0.80 | CYP3A4 (0.38) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL30987348 | 0.79 | TNF (0.39) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL24879127 | 0.79 | TNF (0.39) | CYP3A4TSHRTDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024147703-A1 | SHP2 INHIBITOR AND USES THEREOF | 주식회사 카나프테라퓨틱스 | 2024-07-11 | — | — | WO | disclosed |