SCHEMBL30987326

SCHEMBL30987326

[2H]C([2H])([2H])n1cnc2ccc(Br)c(Cl)c2c1=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRAF P15056 17/20 0.36
PTPN11 Q06124 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29969954 0.91 BRAF (0.42) BRAF
SCHEMBL29561883 0.83 BRAF (0.35) BRAF
SCHEMBL22831909 0.83 BRAF (0.35) BRAF
SCHEMBL31559939 0.82 BRAF (0.36) BRAF
SCHEMBL24878852 0.74 ESR2 (0.50) BRAF
SCHEMBL29562057 0.73 BRAF (0.41) BRAF
SCHEMBL22831813 0.73 BRAF (0.41) BRAF
SCHEMBL31723352 0.72 BRAF (0.38) BRAF
SCHEMBL24879123 0.72 BRAF (0.46) BRAF
SCHEMBL22831804 0.72 BRAF (0.42) BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647433-A1 SHP2 INHIBITOR AND USES THEREOF Kanaph Therapeutics Inc. (KR) 2025-11-12 EP disclosed
WO-2024147703-A1 SHP2 INHIBITOR AND USES THEREOF 주식회사 카나프테라퓨틱스 2024-07-11 WO disclosed