Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 5/20 | 0.35 |
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | CDK1 | P06493 | 4/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723357 | 0.85 | TNF (0.36) | BRAFHSD17B13GSK3AGSK3BCDK1 | |
| SCHEMBL24879123 | 0.77 | BRAF (0.46) | BRAFHSD17B13TNF | |
| SCHEMBL24879033 | 0.76 | CLK1 (0.48) | BRAFHSD17B13TNF | |
| SCHEMBL31723359 | 0.75 | BRAF (0.34) | BRAFHSD17B13GSK3AGSK3BCDK1 | |
| SCHEMBL29969954 | 0.75 | BRAF (0.42) | BRAF | |
| SCHEMBL22832076 | 0.74 | BRAF (0.47) | BRAFGSK3AGSK3BCDK1CCNB1 | |
| SCHEMBL30987319 | 0.74 | MCL1 (0.58) | TRPA1TNFMCL1 | |
| SCHEMBL30987326 | 0.72 | BRAF (0.36) | BRAF | |
| SCHEMBL30987315 | 0.72 | USP7 (0.45) | HSD17B13 | |
| SCHEMBL20786904 | 0.71 | MCL1 (0.46) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |