Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14421241 | 1.00 | KCNMA1 (0.60) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL21512532 | 0.84 | KCNMA1 (0.50) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL13338049 | 0.81 | KCNMA1 (0.50) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL25581089 | 0.80 | SMN1; SMN2 (0.56) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL23840194 | 0.79 | KCNMA1 (0.64) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL25862494 | 0.79 | KCNMA1 (0.64) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL19142983 | 0.79 | SMN1; SMN2 (0.48) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL21416845 | 0.77 | KCNMA1 (0.57) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL12859913 | 0.77 | SMN1; SMN2 (0.57) | KCNMA1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL14146414 | 0.76 | KCNMA1 (0.49) | KCNMA1ALDH1A1LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |