Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987489 | 0.86 | KMT2A (0.52) | KMT2AMEN1KDM4ETSHRNPSR1 | |
| SCHEMBL30987486 | 0.86 | KMT2A (0.52) | KMT2AMEN1KDM4ETSHRNPSR1 | |
| SCHEMBL30987494 | 0.86 | KMT2A (0.56) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL30987497 | 0.86 | KMT2A (0.52) | KMT2AMEN1KDM4ETSHRNPSR1 | |
| SCHEMBL30987492 | 0.82 | KMT2A (0.48) | KMT2AMEN1KDM4ETSHRNPSR1 | |
| SCHEMBL13013046 | 0.74 | KMT2A (0.64) | KMT2AMEN1KDM4ETSHRNPSR1 | |
| SCHEMBL23657198 | 0.73 | KDM4E (0.62) | KMT2AMEN1KDM4EGLATSHR | |
| SCHEMBL13180324 | 0.73 | KDM4E (0.62) | KMT2AMEN1KDM4EGLATSHR | |
| SCHEMBL23657255 | 0.73 | KDM4E (0.62) | KMT2AMEN1KDM4EGLATSHR | |
| SCHEMBL25493697 | 0.72 | KDM4E (0.57) | KMT2AMEN1KDM4EGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139842-A | Oximes and their use in the treatment of GBA related diseases | 泽拉丹麦有限公司 | 2024-06-04 | — | — | CN | disclosed |