Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987489 | 1.00 | KMT2A (0.52) | KMT2AMEN1TSHRNPSR1ATM | |
| SCHEMBL30987497 | 1.00 | KMT2A (0.52) | KMT2AMEN1TSHRNPSR1ATM | |
| SCHEMBL30987494 | 0.88 | KMT2A (0.56) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL30987491 | 0.86 | KMT2A (0.51) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL30987499 | 0.85 | KMT2A (0.46) | KMT2AMEN1TSHRATMHTT | |
| SCHEMBL30987492 | 0.83 | KMT2A (0.48) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL30987500 | 0.80 | HTT (0.43) | KMT2AMEN1TSHRATMHTT | |
| SCHEMBL13013046 | 0.75 | KMT2A (0.64) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL24319645 | 0.72 | KMT2A (0.56) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL68147 | 0.72 | KMT2A (0.64) | KMT2AMEN1TSHRATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139842-A | Oximes and their use in the treatment of GBA related diseases | 泽拉丹麦有限公司 | 2024-06-04 | — | — | CN | disclosed |