Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601048 | 0.95 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL2707102 | 0.95 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL204974 | 0.95 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL25428390 | 0.87 | HSD17B10 (0.52) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL31048244 | 0.85 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL2307400 | 0.85 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL3156952 | 0.85 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL15317017 | 0.85 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL18787688 | 0.84 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL18787687 | 0.84 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2ALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676929-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2026-01-14 | — | — | EP | disclosed |
| EP-4638447-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | Dark Blue Therapeutics Ltd (GB) | 2025-10-29 | — | — | EP | disclosed |
| CN-119751486-A | PRMT5 inhibitor and application thereof | 赛岚(杭州)生物医药科技有限公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024188906-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2024-09-19 | — | — | WO | disclosed |
| WO-2024133560-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | DARK BLUE THERAPEUTICS LTD (GB) | 2024-06-27 | — | — | WO | disclosed |