SCHEMBL3098922

SCHEMBL3098922

O=c1oc2ccccc2c(=O)n1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.62
ALDH1A1 P00352 5/20 0.51
PPARG P37231 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
NR2E3 Q9Y5X4 1/20 0.51
NCOR2 Q9Y618 1/20 0.51
SMN1; SMN2 Q16637 5/20 0.49
LMNA P02545 4/20 0.49
HTR1A P08908 2/20 0.48
NPSR1 Q6W5P4 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 2/20 0.45
HSD17B10 Q99714 2/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 2/20 0.45
GLA P06280 1/20 0.45
CYP3A4 P08684 1/20 0.45
PGAM1 P18669 1/20 0.45
MAOA P21397 1/20 0.45
CASP1 P29466 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3104203 0.86 ALDH1A1 (0.57) MAPK1ALDH1A1PPARGRXFP1NR2E3
SCHEMBL18196442 0.86 NPSR1 (0.69) MAPK1NPSR1L3MBTL1CA9POLB
SCHEMBL18196703 0.81 NPSR1 (0.51) MAPK1NPSR1L3MBTL1KDM4ECA9
SCHEMBL8777824 0.80 MAPK1 (0.47) MAPK1ALDH1A1PPARGRXFP1NR2E3
SCHEMBL9638035 0.80 NPC1 (0.54) MAPK1ALDH1A1PPARGRXFP1NR2E3
SCHEMBL18196591 0.78 MYC (0.50) MAPK1ALDH1A1NPSR1L3MBTL1KDM4E
SCHEMBL4622801 0.77 TNKS (0.55) MAPK1ALDH1A1SMN1; SMN2LMNAHTR1A
SCHEMBL23260300 0.76 MAPK1 (0.59) MAPK1ALDH1A1PPARGRXFP1NR2E3
SCHEMBL171826 0.73 KDM4E (0.48) MAPK1ALDH1A1SMN1; SMN2HTR1ANPSR1
SCHEMBL11148469 0.73 FEN1 (0.50) MAPK1ALDH1A1SMN1; SMN2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4716701-A1 USE OF AMIVANTAMAB TO TREAT COLORECTAL CANCER Janssen Biotech, Inc. (US) 2026-04-01 EP disclosed
US-20100255934-A1 COMPOSITIONS FOR GOLF EQUIPMENT ACUSHNET COMPANY 2010-10-07 US disclosed
US-7709590-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2010-05-04 US disclosed
US-7550549-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2009-06-23 US disclosed
US-7417106-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-08-26 US disclosed
US-20080188326-A1 Compositions for Golf Equipment ACUSHNET COMPANY 2008-08-07 US disclosed
US-7378483-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2008-05-27 US disclosed
US-20080064527-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-03-13 US disclosed
US-7276570-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2007-10-02 US disclosed
US-7265195-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2007-09-04 US disclosed
US-20050119451-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-06-02 US disclosed
US-20050004325-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-06 US disclosed
US-20040220356-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220377-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220378-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220373-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220376-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220371-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220357-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220375-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed