Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009669 | 0.72 | RPS6KA5 (0.40) | RPS6KA5TYRO3DYRK1BKDM4EMAPT | |
| SCHEMBL22518633 | 0.71 | RPS6KA5 (0.45) | RPS6KA5TYRO3DYRK1BKDM4E | |
| SCHEMBL1446801 | 0.68 | RPS6KA5 (0.40) | RPS6KA5TYRO3DYRK1BKDM4E | |
| SCHEMBL12120921 | 0.68 | TYRO3 (0.42) | RPS6KA5TYRO3DYRK1BKDM4E | |
| SCHEMBL30475606 | 0.68 | TYRO3 (0.42) | RPS6KA5TYRO3DYRK1BKDM4E | |
| SCHEMBL14842412 | 0.68 | AXL (0.47) | RPS6KA5TYRO3DYRK1BKDM4E | |
| SCHEMBL30989389 | 0.68 | TYRO3 (0.36) | TYRO3DYRK1BKDM4E | |
| SCHEMBL23725349 | 0.65 | KMT2A (0.47) | RPS6KA5TYRO3DYRK1BKDM4EMAPT | |
| SCHEMBL30899087 | 0.65 | LRRK2 (0.47) | RPS6KA5TYRO3DYRK1B | |
| SCHEMBL28274262 | 0.65 | LRRK2 (0.47) | RPS6KA5TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359638-A | Compound serving as RET kinase inhibitor and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-19 | — | — | CN | disclosed |