Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25887465 | 1.00 | NTRK1 (0.31) | NTRK1CSF1RNTRK2BRD4GRIN1 | |
| SCHEMBL30989708 | 0.88 | CARM1 (0.31) | — | |
| SCHEMBL25887456 | 0.88 | CARM1 (0.31) | — | |
| SCHEMBL30989696 | 0.88 | POLB (0.42) | GRIN1GRIN2BPOLB | |
| SCHEMBL25887368 | 0.88 | POLB (0.42) | GRIN1GRIN2BPOLB | |
| SCHEMBL31194302 | 0.86 | POLB (0.35) | GRIN1GRIN2BPOLB | |
| SCHEMBL25885742 | 0.86 | BRD4 (0.31) | BRD4GRIN1GRIN2B | |
| SCHEMBL30989653 | 0.86 | BRD4 (0.31) | BRD4GRIN1GRIN2B | |
| SCHEMBL25314531 | 0.85 | AKT1 (0.33) | BRD4GRIN1GRIN2B | |
| SCHEMBL25887514 | 0.81 | CYP11B1 (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355004-A | Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives | 勃林格殷格翰动物保健有限公司 | 2024-07-16 | — | — | CN | disclosed |