Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25887368 | 0.93 | POLB (0.42) | POLBDGAT1GRIN1GRIN2B | |
| SCHEMBL30989696 | 0.93 | POLB (0.42) | POLBDGAT1GRIN1GRIN2B | |
| SCHEMBL21586180 | 0.90 | POLB (0.39) | POLB | |
| SCHEMBL25887465 | 0.86 | NTRK1 (0.31) | POLBGRIN1GRIN2B | |
| SCHEMBL30989675 | 0.86 | NTRK1 (0.31) | POLBGRIN1GRIN2B | |
| SCHEMBL31194290 | 0.85 | POLB (0.35) | POLB | |
| SCHEMBL29431612 | 0.85 | POLB (0.43) | POLB | |
| SCHEMBL14684616 | 0.85 | POLB (0.43) | POLB | |
| SCHEMBL25314531 | 0.85 | AKT1 (0.33) | MAP4K1GRIN1GRIN2B | |
| SCHEMBL25885639 | 0.85 | POLB (0.33) | POLBGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175557-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFOXIME-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |