Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30990044 | 1.00 | MAPK1 (0.41) | MAPK1MAP3K5PIK3C3GPBAR1AURKA | |
| SCHEMBL30989968 | 0.89 | HPGD (0.34) | MAPK1MAP3K5AURKARPS6KB1AOC3 | |
| SCHEMBL30989829 | 0.89 | HPGD (0.34) | MAPK1MAP3K5AURKARPS6KB1AOC3 | |
| SCHEMBL30989878 | 0.82 | PIK3C3 (0.38) | MAP3K5PIK3C3GPBAR1GPR6MEN1 | |
| SCHEMBL30989919 | 0.82 | PIK3C3 (0.38) | MAP3K5PIK3C3GPBAR1GPR6MEN1 | |
| SCHEMBL30989928 | 0.82 | PIK3C3 (0.44) | MAP3K5PIK3C3GPBAR1GPR6PTGER4 | |
| SCHEMBL30990011 | 0.82 | PIK3C3 (0.44) | MAP3K5PIK3C3GPBAR1GPR6PTGER4 | |
| SCHEMBL30989809 | 0.80 | PIK3C3 (0.39) | MAP3K5PIK3C3GPBAR1GPR6PTGER4 | |
| SCHEMBL30989899 | 0.80 | PIK3C3 (0.39) | MAP3K5PIK3C3GPBAR1GPR6PTGER4 | |
| SCHEMBL30989772 | 0.80 | PTGER4 (0.43) | MAPK1PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |