Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL27569699 | 0.88 | LMNA (0.50) | LMNATSHRMEN1CYP2C19RECQL | |
| SCHEMBL31019825 | 0.88 | LMNA (0.54) | TDP1LMNATSHRMEN1CYP2C19 | |
| SCHEMBL128684 | 0.88 | — | — | |
| Ethane SCHEMBL28426694 | 0.85 | LMNA (0.52) | TDP1LMNATSHRMEN1CYP2C19 | |
| SCHEMBL28318585 | 0.85 | — | — | |
| Bromide SCHEMBL30338324 | 0.85 | — | — | |
| Propane SCHEMBL28528148 | 0.85 | LMNA (0.52) | TDP1LMNATSHRMEN1CYP2C19 | |
| SCHEMBL28757042 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL29626546 | 0.85 | LMNA (0.52) | TDP1LMNATSHRMEN1CYP2C19 | |
| Hydrogen Sulfide SCHEMBL28141299 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10103345-B2 | Quantum dot light-emitting diode and light-emitting display device using the diode | LG DISPLAY CO., LTD. (KR) | 2018-10-16 | — | — | US | disclosed |
| US-20180138434-A1 | QUANTUM DOT LIGHT-EMITTING DIODE AND LIGHT-EMITTING DISPLAY DEVICE USING THE DIODE | LG DISPLAY CO., LTD. (KR) | 2018-05-17 | — | — | US | disclosed |
| CN-1873534-B | Photosensitive resin composition, method of manufacturing a thin-film transistor substrate, and method of manufacturing a common electrode substrate using the same | SAMSUNG ELECTRONICS CO LTD | 2011-09-28 | — | — | CN | disclosed |
| US-7799509-B2 | Photosensitive resin composition, method of manufacturing a thin-film transistor substrate, and method of manufacturing a common electrode substrate using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2010-09-21 | — | — | US | disclosed |
| US-20060275700-A1 | Photosensitive resin composition, method of manufacturing a thin-film transistor substrate, and method of manufacturing a common electrode substrate using the same | SAMSUNG ELECTRONICS CO., LTD. | 2006-12-07 | — | — | US | disclosed |
| CN-1873534-A | Photosensitive resin composition, method of manufacturing a thin-film transistor substrate, and method of manufacturing a common electrode substrate using the same | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-12-06 | — | — | CN | disclosed |
| US-6686120-B2 | THERMAL ACID GENERATOR AND A METHOD OF FORMING A PATTERN USING THE SAME. THE PHOTORESIST COMPOSITION INCLUDES ABOUT 100 PARTS BY WEIGHT OF AN ALKALI-SOLUBLE ACRYL COPOLYMER, ABOUT 5-100 PARTS BY WEIGHT OF 1,2-QUINONEDIAZIDE COMPOUND, ABOUT | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2004-02-03 | — | — | US | disclosed |
| US-20030134222-A1 | Photoresist composition and method of forming pattern using the same | SAMSUNG ELECTRONICS CO., LTD. | 2003-07-17 | — | — | US | disclosed |