SCHEMBL30990366 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PDCD1	Q15116	1/20	0.44

▸	CD274	Q9NZQ7	1/20	0.44

▸	CCR3	P51677	2/20	0.41

▸	TMEM97	Q5BJF2	2/20	0.40

▸	RAD52	P43351	1/20	0.40

▸	HRH3	Q9Y5N1	7/20	0.38

▸	BCHE	P06276	1/20	0.37

▸	HRH2	P25021	2/20	0.36

▸	HRH1	P35367	2/20	0.36

▸	DRD2	P14416	1/20	0.36

▸	DRD3	P35462	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30990368	0.95	PDCD1 (0.45)	PDCD1CD274CCR3HRH3HRH2
SCHEMBL167048	0.88	PDCD1 (0.40)	PDCD1CD274HRH3
SCHEMBL166996	0.88	PDCD1 (0.40)	PDCD1CD274HRH3
SCHEMBL166995	0.88	PDCD1 (0.40)	PDCD1CD274HRH3
SCHEMBL21068738	0.85	TP53 (0.44)	CCR3
SCHEMBL28960041	0.76	PDCD1 (0.49)	PDCD1CD274HRH3HRH2HRH1
SCHEMBL2755862	0.75	RAD52 (0.53)	RAD52HRH3
SCHEMBL7068538	0.74	RAD52 (0.55)	RAD52HRH3
SCHEMBL30923341	0.73	PDCD1 (0.40)	PDCD1CD274HRH3
SCHEMBL21815092	0.73	GNAI3 (0.46)	CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024140850-A1	PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF	苏州必扬医药科技有限公司	2024-07-04	—	—	WO	disclosed