Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 14/20 | 0.54 |
| ▸ | KDR | P35968 | 9/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.44 |
| ▸ | PRKDC | P78527 | 6/20 | 0.44 |
| ▸ | ABL1 | P00519 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | HCK | P08631 | 5/20 | 0.44 |
| ▸ | SRC | P12931 | 5/20 | 0.44 |
| ▸ | MTOR | P42345 | 5/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 5/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30990449 | 1.00 | RET (0.54) | RETKDRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL30990436 | 0.82 | RET (0.54) | RETKDREGFRSRC | |
| SCHEMBL30990425 | 0.79 | EGFR (0.66) | RETEGFR | |
| SCHEMBL30990430 | 0.79 | RET (0.53) | RETEGFR | |
| SCHEMBL30990450 | 0.79 | RET (0.51) | RETKDREGFR | |
| SCHEMBL30381942 | 0.78 | RET (0.75) | RETKDRHCK | |
| SCHEMBL21179050 | 0.78 | RET (0.75) | RETKDRHCK | |
| Hydrochloric Acid SCHEMBL31640040 | 0.78 | RET (0.51) | RETKDRPIK3CDPIK3CAPIK3CB | |
| SCHEMBL14139056 | 0.77 | BTK (0.64) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30990426 | 0.77 | RET (0.51) | RETEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665720-A2 | ISOINDOLINONE GLUTARIMIDE AND PHENYL GLUTARIMIDE ANALOGS AS DEGRADERS OF RET KINASE | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173832-A2 | ISOINDOLINONE GLUTARIMIDE AND PHENYL GLUTARIMIDE ANALOGS AS DEGRADERS OF RET KINASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |