SCHEMBL30990840

SCHEMBL30990840

Brc1ccc2c3c(cccc13)-c1cc3ccccc3cc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
ALDH1A1 P00352 4/20 0.57
TSHR P16473 3/20 0.57
MAPK1 P28482 3/20 0.57
HSD17B10 Q99714 3/20 0.57
HPGD P15428 2/20 0.57
CASP1 P29466 2/20 0.57
HIF1A Q16665 2/20 0.57
TP53 P04637 1/20 0.57
CASP7 P55210 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.55
HKDC1 Q2TB90 1/20 0.49
CYP1B1 Q16678 13/20 0.46
POLB P06746 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2198488 1.00 CYP1A2 (0.59) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL20598536 0.86 CYP1A2 (0.61) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL30345509 0.86 CYP1A2 (0.63) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL663504 0.86 CYP1A2 (0.63) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL12025752 0.85 CYP1A2 (0.49) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL27657670 0.84 CYP1A2 (0.51) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
Fluoranthene SCHEMBL27657669 0.84 CYP1A2 (0.51) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL8010799 0.84 ALDH1A1 (0.67) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL20259109 0.81 CYP1A2 (0.51) CYP1A2ALDH1A1TSHRMAPK1HSD17B10
SCHEMBL12200333 0.81 ALDH1A1 (0.56) CYP1A2ALDH1A1TSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115427400-B Compound and organic light emitting device comprising the same 株式会社LG化学 2024-08-02 CN disclosed