Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 5/20 | 0.39 |
| ▸ | KRAS | P01116 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723304 | 0.91 | SOS1 (0.43) | SOS1KRASIDO1TDO2PDE2A | |
| SCHEMBL21132649 | 0.91 | SOS1 (0.43) | SOS1KRASIDO1TDO2PDE2A | |
| SCHEMBL23412612 | 0.91 | SOS1 (0.43) | SOS1KRASIDO1TDO2PDE2A | |
| Hydrochloric Acid SCHEMBL25300330 | 0.89 | SOS1 (0.42) | SOS1KRASIDO1TDO2PDE2A | |
| Hydrochloric Acid SCHEMBL23577813 | 0.89 | SOS1 (0.42) | SOS1KRASIDO1TDO2PDE2A | |
| Hydrochloric Acid SCHEMBL29755614 | 0.89 | SOS1 (0.42) | SOS1KRASIDO1TDO2PDE2A | |
| SCHEMBL30991137 | 0.85 | SOS1 (0.41) | SOS1KRASIDO1TDO2PDE2A | |
| Trifluoroacetic Acid SCHEMBL27094787 | 0.83 | SOS1 (0.41) | SOS1KRASIDO1TDO2PDE2A | |
| SCHEMBL30991168 | 0.82 | IDO1 (0.49) | IDO1TDO2PDE2AP2RX7 | |
| SCHEMBL30991163 | 0.82 | KRAS (0.35) | SOS1KRASIDO1TDO2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4667464-A1 | AZOLYLPYRIDINE PYRIDAZINONE AMIDE AS SOS1 INHIBITOR | Cyrus Therapeutics Inc. (KR) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024172632-A1 | AZOLYLPYRIDINE PYRIDAZINONE AMIDE AS SOS1 INHIBITOR | (주) 사이러스테라퓨틱스 | 2024-08-22 | — | — | WO | disclosed |