Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30991164 | 1.00 | KRAS (0.35) | KRASSOS1IDO1TDO2CYP1A2 | |
| SCHEMBL23412612 | 0.88 | SOS1 (0.43) | KRASSOS1IDO1TDO2CYP1A2 | |
| SCHEMBL21132649 | 0.88 | SOS1 (0.43) | KRASSOS1IDO1TDO2CYP1A2 | |
| SCHEMBL29723304 | 0.88 | SOS1 (0.43) | KRASSOS1IDO1TDO2CYP1A2 | |
| Hydrochloric Acid SCHEMBL29755614 | 0.86 | SOS1 (0.42) | KRASSOS1IDO1TDO2CYP1A2 | |
| Hydrochloric Acid SCHEMBL25300330 | 0.86 | SOS1 (0.42) | KRASSOS1IDO1TDO2CYP1A2 | |
| Hydrochloric Acid SCHEMBL23577813 | 0.86 | SOS1 (0.42) | KRASSOS1IDO1TDO2CYP1A2 | |
| SCHEMBL30991139 | 0.83 | IDO1 (0.37) | KRASSOS1IDO1TDO2CYP1A2 | |
| SCHEMBL30991093 | 0.82 | SOS1 (0.39) | KRASSOS1IDO1TDO2P2RX7 | |
| Trifluoroacetic Acid SCHEMBL27094787 | 0.80 | SOS1 (0.41) | KRASSOS1IDO1TDO2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4667464-A1 | AZOLYLPYRIDINE PYRIDAZINONE AMIDE AS SOS1 INHIBITOR | Cyrus Therapeutics Inc. (KR) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024172632-A1 | AZOLYLPYRIDINE PYRIDAZINONE AMIDE AS SOS1 INHIBITOR | (주) 사이러스테라퓨틱스 | 2024-08-22 | — | — | WO | disclosed |