Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20702651 | 1.00 | NPFFR2 (0.50) | NPFFR2KDRLMNAPDK1P2RX7 | |
| SCHEMBL24959794 | 0.87 | NOTUM (0.42) | KDRHDAC1MAPTALDH1A1NOTUM | |
| SCHEMBL20702662 | 0.85 | KDR (0.50) | NPFFR2KDRPDK1SLC6A3HSD11B1 | |
| SCHEMBL30298640 | 0.83 | GSK3B (0.54) | NPFFR2KDRPDK1SLC6A3HSD11B1 | |
| SCHEMBL1726226 | 0.83 | GSK3B (0.54) | NPFFR2KDRPDK1SLC6A3HSD11B1 | |
| SCHEMBL4097529 | 0.83 | NPFFR2 (0.47) | NPFFR2KDRPDK1SLC6A3 | |
| SCHEMBL30173749 | 0.83 | NPFFR2 (0.47) | NPFFR2KDRPDK1SLC6A3 | |
| SCHEMBL23792959 | 0.82 | NPFFR2 (0.47) | NPFFR2KDRLMNAPDK1SLC6A3 | |
| SCHEMBL21776928 | 0.81 | KDR (0.48) | NPFFR2KDRLMNAPDK1SLC6A3 | |
| SCHEMBL2074095 | 0.81 | TAS1R3 (0.49) | MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420559-B | Deuterated oxadiazinone compound and application thereof | 上海超阳药业有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-118420559-A | Deuterated oxadiazinone compound and application thereof | 上海超阳药业有限公司 | 2024-08-02 | — | — | CN | disclosed |