Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24414579 | 1.00 | CDC7 (0.41) | CDC7ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL24414575 | 0.79 | CDC7 (0.41) | CDC7ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL30991780 | 0.79 | KRAS (0.42) | TSHRKMT2AKRASSOS1HTR7 | |
| SCHEMBL24414580 | 0.79 | KRAS (0.42) | TSHRKMT2AKRASSOS1HTR7 | |
| SCHEMBL29587634 | 0.79 | CDC7 (0.41) | CDC7ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL25423499 | 0.78 | ALDH1A1 (0.42) | CDC7ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL25424064 | 0.77 | ALDH1A1 (0.40) | CDC7ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL30487727 | 0.77 | ALDH1A1 (0.42) | CDC7ALDH1A1TSHRKDM4EHSD17B10 | |
| SCHEMBL29288341 | 0.77 | HTR2C (0.39) | TSHRKRASSOS1HTR7BRD4 | |
| SCHEMBL25424956 | 0.76 | ALDH1A1 (0.46) | CDC7ALDH1A1TSHRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113474340-B | Novel isoindolinone substituted indoles and derivatives as RAS inhibitors | 勃林格殷格翰国际有限公司 | 2024-07-23 | — | — | CN | disclosed |