Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 15/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 14/20 | 0.44 |
| ▸ | CDK2 | P24941 | 9/20 | 0.44 |
| ▸ | CDK4 | P11802 | 6/20 | 0.44 |
| ▸ | CCND1 | P24385 | 6/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.44 |
| ▸ | CDK3 | Q00526 | 5/20 | 0.44 |
| ▸ | CDK1 | P06493 | 4/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 2/20 | 0.32 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30992021 | 0.81 | CDK9 (0.35) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL29330387 | 0.79 | CDK2 (0.34) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL30992058 | 0.77 | CDK9 (0.37) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL30992064 | 0.75 | CCNT1 (0.39) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL29333162 | 0.75 | CCNT1 (0.34) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL30992076 | 0.74 | CCNT1 (0.38) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL30992073 | 0.74 | CCNT1 (0.38) | CDK9CCNT1CDK2CDK4CCND1 | |
| Hydrochloric Acid SCHEMBL30991966 | 0.74 | HTR2C (0.40) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL30991898 | 0.74 | HTR2A (0.33) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL30991896 | 0.73 | CCNT1 (0.40) | CDK9CCNT1CDK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151112-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR | 주식회사 티움바이오 | 2024-07-18 | — | — | WO | claimed |