Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30991970 | 1.00 | CCNT1 (0.33) | CCNT1CDK9CDK2CDK1CDK4 | |
| SCHEMBL30991983 | 1.00 | CCNT1 (0.33) | CCNT1CDK9CDK2CDK1CDK4 | |
| Hydrochloric Acid SCHEMBL30992069 | 0.99 | CCNT1 (0.32) | CCNT1CDK9CDK2CDK1CDK4 | |
| SCHEMBL30991992 | 0.94 | — | — | |
| SCHEMBL30991964 | 0.93 | CCNT1 (0.32) | CCNT1CDK9CDK2CDK1CDK4 | |
| SCHEMBL30991887 | 0.92 | CDK9 (0.33) | CCNT1CDK9CDK2CDK1CDK4 | |
| SCHEMBL29333266 | 0.91 | CDK9 (0.36) | CCNT1CDK9CDK2CDK1CDK4 | |
| Hydrochloric Acid SCHEMBL30991967 | 0.90 | CDK9 (0.35) | CCNT1CDK9CDK2CDK1CDK4 | |
| SCHEMBL30992052 | 0.90 | CCNT1 (0.32) | CCNT1CDK9CDK2CDK1CDK4 | |
| SCHEMBL29333292 | 0.90 | CDK2 (0.31) | CCNT1CDK9CDK2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151112-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR | 주식회사 티움바이오 | 2024-07-18 | — | — | WO | claimed |
| WO-2024151112-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR | 주식회사 티움바이오 | 2024-07-18 | — | — | WO | disclosed |