SCHEMBL309925

SCHEMBL309925

Nc1ncccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30258630 1.00
Hydrochloric Acid SCHEMBL2815657 0.97
Trifluoroacetic Acid SCHEMBL2261846 0.82 NAPRT (0.50)
SCHEMBL28483689 0.80 KDM4E (0.49)
SCHEMBL27930554 0.75 KDM4E (0.53)
SCHEMBL29809843 0.74
SCHEMBL312305 0.74
SCHEMBL19791994 0.72 BACE1 (0.53)
SCHEMBL88338 0.72
SCHEMBL15624391 0.72 TDP1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624393-A Pyridyl Schiff base anionic inulin quaternary ammonium salt and preparation method and application thereof 中国科学院烟台海岸带研究所 2024-03-01 CN claimed
US-20220194928-A1 NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE UNIV KOREA RES & BUS FOUND (KR) 2022-06-23 US claimed
US-20190119261-A1 NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2019-04-25 US claimed
EP-2336315-A2 Enzymatic encoding methods for efficient synthesis of large libraries Nuevolution A/S (DK) 2011-06-22 EP claimed
CN-122094938-A Process for preparing 3, 5-difluoro-2-pyridinecarboxamide 2026-05-26 CN disclosed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
CN-117534671-B Method for synthesizing imidazo [1, 2-alpha ] pyridine derivative by using titanocene dichloride as catalyst 宁夏师范学院 2026-05-12 CN disclosed
EP-4703359-A1 IMIDAZOPYRIDINE OR IMIDAZOPYRAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Shanghai Simr Biotechnology Co., Ltd. (CN) 2026-03-04 EP disclosed
US-12534463-B2 Substituted tricyclic compounds as FGFR inhibitors INCYTE CORPORATION (US) 2026-01-27 US disclosed
EP-4651944-A1 INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF Ventus Therapeutics U.S., Inc. (US) 2025-11-26 EP disclosed
US-20250353820-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS NOVARTIS AG (CH) 2025-11-20 US disclosed
US-20250325548-A1 TUMOR SUPPRESSOR P73 TRANSCRIPTIONALLY REGULATES C-FLIP TO IMPEDE ITS PRIMING OF EXTRINSIC APOPTOSIS WHILE AN EXAMPLE SWITCHER COMPOUND CB-7587351 DEGRADES C-FLIP PROTEIN UNIV BROWN (US) 2025-10-23 US disclosed
EP-0958297-A1 1-ARYL-1,8-NAPHTHYLIDIN-4-ONE DERIVATIVE AS TYPE IV PHOSPHODIESTERASE INHIBITOR SUNTORY LIMITED (JP) 1999-11-24 EP disclosed
WO-1999007704-A1 1-ARYL-1,8-NAPHTHYLIDIN-4-ONE DERIVATIVE AS TYPE IV PHOSPHODIESTERASE INHIBITOR SUNTORY LIMITED (JP) 1999-02-18 WO disclosed
EP-0160252-B1 Antibacterial compounds Takeda Chemical Industries, Ltd. (JP) 1992-08-26 EP disclosed
US-4788185-A Cephalosporin compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-11-29 US disclosed
EP-0160252-A2 Antibacterial compounds Takeda Chemical Industries, Ltd. (JP) 1985-11-06 EP disclosed
US-4134975-A PYRIDO(1,2,-D)(1,4,6)BENZOXADIAZOCINES OR PYRIDO(1,2,-C)(1,3,5)BENZOXADIAZEPINES E. R. SQUIBB & SONS, INC. (US) 1979-01-16 US disclosed
US-3995042-A MUSCLE RELAXANTS, CENTRAL NERVOUS SYSTEM STIMULANTS E. R. SQUIBB & SONS, INC. (US) 1976-11-30 US disclosed
US-3957806-A STIMULANTS, MUSCLE RELAXANTS E. R. SQUIBB & SONS, INC. (US) 1976-05-18 US disclosed