SCHEMBL30992903

SCHEMBL30992903

COC(=O)c1ccc(-c2cc3c(cc2C(F)F)NCCC3)cn1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CREBBP Q92793 6/20 0.41
▸ BRD4 O60885 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ PPARG P37231 3/20 0.38
▸ PPARD Q03181 3/20 0.38
▸ PPARA Q07869 3/20 0.38
▸ MAPK1 P28482 1/20 0.37
▸ HPGD P15428 1/20 0.36
▸ AKT1 P31749 2/20 0.35
▸ AKT2 P31751 1/20 0.35
▸ DYRK1A Q13627 1/20 0.35
▸ PARP1 P09874 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ PDE3B Q13370 1/20 0.34
▸ PDE3A Q14432 1/20 0.34
▸ CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30993155 0.94 CREBBP (0.39) CREBBPBRD4GAAMAPK1HPGD
SCHEMBL24316742 0.88 CREBBP (0.52) CREBBPBRD4MAPT
SCHEMBL30993509 0.86 GAA (0.40) GAAPPARGPPARDPPARAMAPK1
SCHEMBL30993069 0.84 MAPK1 (0.39) GAAPPARGPPARDPPARAMAPK1
SCHEMBL30992866 0.84 GAA (0.43) GAAPPARGPPARDPPARAMAPK1
SCHEMBL30992896 0.83 PPARG (0.39) GAAPPARGPPARDPPARAMAPK1
SCHEMBL30992946 0.83 MAPK1 (0.39) CREBBPBRD4MAPK1HPGDDYRK1A
SCHEMBL30993515 0.82 EED (0.37) GAAPPARGPPARDPPARAMAPK1
SCHEMBL31208211 0.77 GAA (0.44) GAAPPARGPPARDPPARAPARP1
SCHEMBL30993135 0.74 CREBBP (0.43) CREBBPBRD4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 — — EP disclosed
WO-2025049976-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-03-06 — — WO disclosed
WO-2025049994-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-03-06 — — WO disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 — — WO disclosed
WO-2024130095-A9 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-08-02 — — WO disclosed
WO-2024130095-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-20 — — WO disclosed
Send feedback