Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 18/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993552 | 0.85 | GPR119 (0.46) | CREBBPBRD4GPR119 | |
| SCHEMBL30992909 | 0.76 | CREBBP (0.69) | CREBBPBRD4 | |
| SCHEMBL30993155 | 0.76 | CREBBP (0.39) | CREBBPBRD4GPR119HPGD | |
| SCHEMBL30993056 | 0.75 | CREBBP (0.69) | CREBBPBRD4 | |
| SCHEMBL30993108 | 0.74 | CREBBP (0.65) | CREBBPBRD4 | |
| SCHEMBL30992903 | 0.74 | CREBBP (0.41) | CREBBPBRD4HPGD | |
| SCHEMBL30993322 | 0.73 | CREBBP (0.48) | CREBBPBRD4 | |
| SCHEMBL30993020 | 0.73 | CREBBP (0.69) | CREBBPBRD4 | |
| SCHEMBL31248801 | 0.72 | CREBBP (0.46) | CREBBPBRD4 | |
| SCHEMBL17794572 | 0.71 | CREBBP (0.59) | CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |