SCHEMBL30993172

SCHEMBL30993172

C#CC[C@H](C)NC(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CTSK P43235 13/20 0.46
CTSS P25774 8/20 0.45
CYP2D6 P10635 1/20 0.44
CTSL P07711 3/20 0.43
CTSB P07858 2/20 0.43
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30993196 1.00 CA1 (0.49) CA1CA2CA7CTSKCTSS
SCHEMBL28356427 0.88 CTSK (0.42) CA1CA2CA7CTSKCTSS
SCHEMBL7854592 0.84 CTSK (0.47) CA1CA2CA7CTSKCTSS
SCHEMBL6326266 0.84 CA1 (0.50) CA1CA2CA7CTSKCTSS
SCHEMBL25166215 0.83 CA1 (0.46) CA1CA2CA7CTSKCTSS
SCHEMBL31059710 0.83 CA1 (0.46) CA1CA2CA7CTSKCTSS
SCHEMBL31059527 0.83 CA1 (0.46) CA1CA2CA7CTSKCTSS
SCHEMBL86185 0.82 CTSK (0.56) CA1CA2CA7CTSKCTSS
SCHEMBL86153 0.82 CTSK (0.56) CA1CA2CA7CTSKCTSS
SCHEMBL4118840 0.82 CTSK (0.56) CA1CA2CA7CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743447-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2026-05-20 EP disclosed
EP-4743178-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2026-05-20 EP disclosed
WO-2025016906-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-01-23 WO disclosed
WO-2025016909-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-01-23 WO disclosed
WO-2024130095-A9 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-08-02 WO disclosed
WO-2024130095-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-20 WO disclosed