Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL189992 | 1.00 | LPL (0.50) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL3690091 | 0.86 | LPL (0.46) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16105038 | 0.85 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL1290153 | 0.85 | LPL (0.51) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL4813256 | 0.85 | CA1 (0.45) | LPLLIPGCA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL31547133 | 0.85 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL24252766 | 0.84 | LPL (0.47) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL60127 | 0.84 | LPL (0.47) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL59080 | 0.82 | LPL (0.53) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL20887537 | 0.82 | LPL (0.46) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |