Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 4/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762504 | 0.92 | DPP4 (0.44) | DPP4DPP8DPP9DPP7ADORA1 | |
| SCHEMBL17868689 | 0.85 | USP2 (0.38) | USP2SMN1; SMN2RECQLADORA1RBP4 | |
| SCHEMBL17868582 | 0.81 | RBP4 (0.39) | ADORA1RBP4NR1H2ESR2HTT | |
| SCHEMBL17868644 | 0.81 | RBP4 (0.39) | ADORA1RBP4NR1H2ESR2HTT | |
| SCHEMBL21237549 | 0.78 | ADORA1 (0.45) | USP2SMN1; SMN2DPP4DPP8DPP9 | |
| SCHEMBL17229883 | 0.78 | ADORA1 (0.45) | USP2SMN1; SMN2ADORA1NR1H2ESR2 | |
| SCHEMBL29899468 | 0.77 | MTOR (0.42) | USP2SMN1; SMN2RECQLADORA1NR1H2 | |
| SCHEMBL17317969 | 0.77 | ADORA1 (0.50) | USP2SMN1; SMN2ADORA1RBP4NR1H2 | |
| SCHEMBL19643783 | 0.77 | ADORA1 (0.44) | USP2SMN1; SMN2ADORA1NR1H2ESR2 | |
| SCHEMBL17317597 | 0.77 | ADORA1 (0.44) | USP2SMN1; SMN2ADORA1RBP4NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |