Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | F11 | P03951 | 11/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 10/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360405 | 0.88 | F11 (0.36) | NOTUMF11KLKB1 | |
| SCHEMBL31174046 | 0.81 | NOTUM (0.43) | NOTUMKCNH2F11KLKB1 | |
| SCHEMBL30995016 | 0.79 | NOTUM (0.41) | NOTUMKCNH2F11KLKB1 | |
| SCHEMBL30622090 | 0.79 | F11 (0.40) | NOTUMKCNH2F11KLKB1 | |
| SCHEMBL30271764 | 0.79 | NOTUM (0.39) | NOTUMKCNH2F11KLKB1 | |
| SCHEMBL16971868 | 0.79 | NOTUM (0.39) | NOTUMKCNH2F11KLKB1 | |
| SCHEMBL16971880 | 0.78 | F11 (0.38) | NOTUMF11KLKB1 | |
| SCHEMBL16971328 | 0.77 | F11 (0.37) | NOTUMF11KLKB1 | |
| SCHEMBL30271846 | 0.77 | F11 (0.37) | NOTUMF11KLKB1 | |
| SCHEMBL16971373 | 0.77 | F11 (0.37) | NOTUMKCNH2F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126046-A | Substituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-04 | — | — | CN | disclosed |