Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12791494 | 1.00 | TRIM24 (0.33) | TRIM24TRIM33MAPK1 | |
| SCHEMBL13606495 | 0.80 | ATR (0.37) | MAPK1 | |
| SCHEMBL29952131 | 0.80 | ATR (0.37) | MAPK1 | |
| SCHEMBL469139 | 0.78 | — | — | |
| SCHEMBL29954519 | 0.76 | ATR (0.33) | MAPK1 | |
| SCHEMBL22090180 | 0.74 | KCNJ1 (0.46) | — | |
| SCHEMBL23213755 | 0.74 | CCR4 (0.39) | — | |
| SCHEMBL21274185 | 0.70 | CCR4 (0.42) | — | |
| SCHEMBL29862850 | 0.70 | CCR4 (0.38) | — | |
| SCHEMBL23250599 | 0.70 | CCR4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654625-B | Heterocyclic and heteroaryl compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-08-06 | — | — | CN | disclosed |