Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23250599 | 1.00 | CCR4 (0.38) | CCR4EDNRALMNAKCNJ1 | |
| SCHEMBL22090180 | 0.75 | KCNJ1 (0.46) | EDNRALMNAKCNJ1 | |
| SCHEMBL11229329 | 0.74 | CCR4 (0.39) | CCR4EDNRA | |
| SCHEMBL8055545 | 0.72 | CCR4 (0.38) | CCR4EDNRALMNA | |
| SCHEMBL30427027 | 0.72 | CCR4 (0.38) | CCR4EDNRALMNA | |
| SCHEMBL29954519 | 0.72 | ATR (0.33) | KCNJ1 | |
| SCHEMBL11223672 | 0.71 | CCR4 (0.38) | CCR4EDNRA | |
| SCHEMBL21274185 | 0.70 | CCR4 (0.42) | CCR4EDNRA | |
| SCHEMBL29862869 | 0.70 | CCR4 (0.42) | CCR4EDNRA | |
| SCHEMBL30995255 | 0.70 | TRIM24 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045037-A1 | HETEROARYL-BIPHENYL AMINES FOR THE TREATMENT OF PD-L1 DISEASES | ChemoCentryx, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |