Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346184 | 0.91 | PTPN11 (0.53) | ERN1PTPN11PARP1CES2CES1 | |
| Ammonia Solution, Strong SCHEMBL30849240 | 0.89 | PTPN11 (0.51) | ERN1PTPN11PARP1CES2CES1 | |
| SCHEMBL29375224 | 0.82 | ERN1 (0.67) | ERN1PTPN11 | |
| Trifluoroacetic Acid SCHEMBL30849231 | 0.80 | PTPN11 (0.45) | ERN1PTPN11PARP1KLK1KLK5 | |
| SCHEMBL23111999 | 0.78 | TTR (0.47) | ERN1PTPN11PARP1SMN1; SMN2HDAC1 | |
| SCHEMBL25376653 | 0.78 | TTR (0.47) | ERN1PTPN11PARP1CES2CES1 | |
| SCHEMBL31227556 | 0.78 | TTR (0.47) | ERN1PTPN11PARP1CES2CES1 | |
| Formic Acid SCHEMBL30995428 | 0.76 | ERN1 (0.41) | ERN1PTPN11PARP1KLK1KLK5 | |
| SCHEMBL1799276 | 0.75 | CES2 (0.64) | ERN1PTPN11PARP1CES2CES1 | |
| SCHEMBL23112092 | 0.75 | PTPN11 (0.44) | ERN1PTPN11PARP1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634169-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | Pfizer Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |