Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27213887 | 0.95 | P2RX7 (0.41) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL29317998 | 0.95 | P2RX7 (0.41) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL29319712 | 0.93 | P2RX7 (0.37) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL27213733 | 0.91 | P2RX7 (0.39) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL29318715 | 0.91 | P2RX7 (0.40) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL30995282 | 0.91 | P2RX7 (0.40) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL29317993 | 0.91 | P2RX7 (0.39) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL27213716 | 0.90 | P2RX7 (0.39) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL27390891 | 0.90 | P2RX7 (0.39) | P2RX7P2RY12KCNH2SMPD1SLC6A9 | |
| SCHEMBL27213785 | 0.90 | P2RX7 (0.40) | P2RX7P2RY12KCNH2SMPD1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634169-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | Pfizer Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127297-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | PFIZER INC. (US) | 2024-06-20 | — | — | WO | disclosed |