Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117305 | 0.80 | NOTUM (0.43) | NOTUMADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL13677502 | 0.79 | NOTUM (0.40) | NOTUMPOLBADORA2AADORA1TDP1 | |
| SCHEMBL29190597 | 0.79 | KDM4E (0.61) | NOTUMPOLBADORA2AADORA1KDM4E | |
| SCHEMBL16595800 | 0.79 | NOTUM (0.40) | NOTUMADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL12730004 | 0.76 | NOTUM (0.41) | NOTUMPOLBADORA2AADORA1KDM4E | |
| SCHEMBL12269133 | 0.76 | NOTUM (0.39) | NOTUMTDP1KDM4EALDH1A1MAPT | |
| SCHEMBL22737499 | 0.76 | KDM4E (0.61) | NOTUMPOLBNR4A2KDM4EALDH1A1 | |
| SCHEMBL22331110 | 0.75 | NOTUM (0.40) | NOTUMKDM4EALDH1A1MAPTNSD2 | |
| SCHEMBL15687166 | 0.75 | NOTUM (0.43) | NOTUMKDM4EALDH1A1MAPTNSD2 | |
| SCHEMBL30162111 | 0.74 | ADORA2A (0.37) | NOTUMADORA2AADORA1ALDH1A1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530224-A | Pyrimidinone compound and application thereof | 深圳安泰维生物医药有限公司 | 2024-08-23 | — | — | CN | disclosed |