Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | FRK | P42685 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29267434 | 1.00 | GRM5 (0.40) | GRM5PARP1NR1H2NR1H3PRKD3 | |
| SCHEMBL29267447 | 0.80 | ERN1 (0.40) | CDK2ERN1 | |
| SCHEMBL29267432 | 0.80 | PARP1 (0.35) | PARP1ERN1TRPV3 | |
| SCHEMBL29267459 | 0.76 | PARP1 (0.36) | PARP1CLK2CLK4ALOX5APFEN1 | |
| SCHEMBL30996273 | 0.76 | PARP1 (0.36) | PARP1CLK2CLK4ALOX5APFEN1 | |
| SCHEMBL29267465 | 0.75 | GRM5 (0.41) | GRM5CLK4ALOX5APFEN1 | |
| SCHEMBL27673922 | 0.74 | NR1H2 (0.60) | NR1H2NR1H3 | |
| SCHEMBL29267457 | 0.73 | SLC22A12 (0.40) | PIM1AKT1FLT3PIM3ERN1 | |
| SCHEMBL30996237 | 0.73 | SLC22A12 (0.40) | PIM1AKT1FLT3PIM3ERN1 | |
| SCHEMBL29267446 | 0.72 | PARP1 (0.41) | GRM5PARP1PRKD3MAP4K4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |