Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254511 | 0.77 | KDM4E (0.48) | ERN1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL2719426 | 0.77 | PARP1 (0.39) | PARP1GRM5KMT2AMEN1ALDH1A1 | |
| SCHEMBL3829932 | 0.75 | CCR1 (0.63) | PARP1ERN1KMT2AMEN1ALDH1A1 | |
| SCHEMBL29267439 | 0.74 | PARP1 (0.41) | PARP1ERN1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10040154 | 0.73 | ALDH1A1 (0.48) | PARP1GRM5KMT2AMEN1ALDH1A1 | |
| SCHEMBL2719152 | 0.73 | HAVCR2 (0.52) | PARP1GRM5KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL843955 | 0.73 | ERN1 (0.50) | PARP1ERN1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2720011 | 0.72 | KMT2A (0.43) | PARP1GRM5KMT2AMEN1CDC7 | |
| SCHEMBL30996271 | 0.72 | GRM5 (0.40) | PARP1GRM5ERN1PRKD3MAP4K4 | |
| SCHEMBL18874674 | 0.71 | ERN1 (0.49) | ERN1KMT2AMEN1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |