Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670461 | 0.72 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL30465895 | 0.72 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL24359166 | 0.70 | KDM4E (0.76) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL11396657 | 0.69 | HTR2C (0.60) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL30670432 | 0.68 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL11396922 | 0.66 | HTR2C (0.44) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL11384017 | 0.66 | HTR2C (0.44) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL11390074 | 0.66 | HTR2C (0.64) | KDM4EALDH1A1HPGDHTTKMT2A | |
| SCHEMBL10512778 | 0.65 | HTR2C (0.68) | KDM4EALDH1A1HPGDHTR2CCYP1A2 | |
| SCHEMBL11288197 | 0.65 | HTR2A (0.51) | KDM4EALDH1A1HPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118556061-A | Disubstituted octahydropyrrolo [3,4-c ] pyrrole methyl ketone derivative and application thereof | 江苏恩华药业股份有限公司 | 2024-08-27 | — | — | CN | disclosed |