Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689597 | 0.88 | DRD3 (0.58) | HRH3DRD3HRH1 | |
| SCHEMBL6652253 | 0.88 | DRD3 (0.58) | HRH3DRD3HRH1KDM4E | |
| SCHEMBL9825515 | 0.87 | DRD3 (0.66) | HRH3DRD3HRH1 | |
| SCHEMBL9826117 | 0.85 | DRD3 (0.76) | HRH3DRD3HRH1 | |
| SCHEMBL29464187 | 0.85 | DRD3 (0.62) | HRH3DRD3HRH1 | |
| SCHEMBL29464188 | 0.85 | DRD3 (0.62) | HRH3DRD3HRH1 | |
| SCHEMBL9825963 | 0.84 | SLC6A4 (0.73) | HRH3DRD3HRH1 | |
| Hydrochloric Acid SCHEMBL9826980 | 0.83 | SLC6A4 (0.71) | HRH3DRD3HRH1 | |
| SCHEMBL10808025 | 0.83 | HRH3 (0.59) | HRH3TLR9TLR7 | |
| SCHEMBL10809994 | 0.83 | HRH3 (0.64) | HRH3DRD3HRH1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221577-A | 2-Phenoxyquinoline derivative, and preparation method and application thereof | 湖南中医药大学 | 2024-06-21 | — | — | CN | disclosed |