Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.46 |
| ▸ | CALCR | P30988 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607506 | 0.90 | APLNR (0.56) | APLNRMC4RPLK1OPRM1OPRK1 | |
| SCHEMBL29606819 | 0.89 | APLNR (0.57) | APLNRMC4RPLK1OPRM1OPRK1 | |
| SCHEMBL29607035 | 0.89 | APLNR (0.55) | APLNRMC4RPLK1OPRM1OPRK1 | |
| SCHEMBL29607754 | 0.89 | APLNR (0.56) | APLNRMC4RPLK1OPRM1OPRK1 | |
| SCHEMBL30537456 | 0.88 | APLNR (0.55) | APLNRMC4ROPRM1OPRK1C5AR1 | |
| SCHEMBL30398324 | 0.88 | APLNR (0.54) | APLNRPLK1OPRM1OPRK1CTSL | |
| SCHEMBL29608111 | 0.87 | APLNR (0.55) | APLNRMC4ROPRM1OPRK1C5AR1 | |
| SCHEMBL29607152 | 0.87 | APLNR (0.55) | APLNRMC4ROPRM1OPRK1C5AR1 | |
| SCHEMBL29608108 | 0.87 | APLNR (0.55) | APLNRMC4ROPRM1OPRK1C5AR1 | |
| SCHEMBL29844803 | 0.87 | APLNR (0.53) | APLNRMC4RPLK1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240230663-A1 | METHODS, COMPOSITIONS, AND SYSTEMS FOR PROFILING OR PREDICTING AN IMMUNE RESPONSE | AVAIL BIO INC (US) | 2024-07-11 | — | — | US | disclosed |