Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19260416 | 0.87 | FFAR1 (0.39) | FFAR1ACACBEGLN1 | |
| SCHEMBL3010045 | 0.84 | FFAR1 (0.37) | FFAR1ACACBEGLN1HDAC8PARP1 | |
| SCHEMBL503735 | 0.81 | HRH1 (0.42) | FFAR1ACACBHDAC8PARP1KEAP1 | |
| SCHEMBL8569361 | 0.81 | FFAR1 (0.41) | FFAR1ACACBALDH1A1 | |
| SCHEMBL19113961 | 0.81 | FFAR1 (0.38) | FFAR1ACACBHDAC8KEAP1 | |
| SCHEMBL1901918 | 0.77 | FFAR1 (0.69) | FFAR1ACACBEGLN1 | |
| SCHEMBL15491230 | 0.76 | HDAC8 (0.33) | FFAR1ACACBEGLN1HDAC8PARP1 | |
| SCHEMBL22031755 | 0.76 | FFAR1 (0.33) | FFAR1EGLN1HDAC8KEAP1 | |
| SCHEMBL22031495 | 0.76 | CCR1 (0.35) | FFAR1EGLN1HDAC8KEAP1 | |
| SCHEMBL31098105 | 0.76 | CCR1 (0.35) | FFAR1EGLN1HDAC8KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153173-A1 | AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-25 | — | — | WO | disclosed |